Pack Size 10 Sachet


Probiotic for immune boost

80% of the body’s immune cells are located in the gastrointestinal system. Studies revealed that Lactobacillus paracasei subspecies paracasei CRL431 induced an immunologic response that provided enhanced systemic protection of cells from virus infections by increasing the production of virus neutralizing antibodies significantly. It is equally effective against bacterial and fungal infections. ResitonTM contains Lactobacillus paracasei subspecies paracasei, clinically proven probiotic strain that colonizes in the intestine and strengthens the natural defense of the body, and stimulates the immune system. ResitonTM is a dietary supplement containing potentially beneficial bacteria. In order to provide health benefits ResitonTM has been developed in accordance with the WHO guidelines.

Clinical Studies
Some strains of orally ingested probiotic bacteria may modulate the immune response and increase antibody titers against enteric infections by bacteria or viruses. Even positive ef­fects of probiotics on respiratory tract infections have been re­ported. A study was conducted with an aim to investigate whether and how probiotics affect the immune response to a standardized entero­virus challenge (polio) and infec­tions not limited to the gastroin­testinal tract in healthy adults. With this aim a method was designed. In a randomized, con­trolled and double-blind study 64 volunteers consumed for 5 weeks chemically acidified clotted milk without bacteria or with Lactobacillus rhamnosus GG or Lactobacillus paracasei CRL431 added. In the second week subjects were vaccinated orally against po­lio 1, 2 and 3. Polio virus neutraliz­ing serum activity, the primary pa­rameter was determined by the standard neutralization test (WHO) before and three times af­ter vaccination. Polio-specific IgA, IgG and IgM were detected by ELISAs. The result was very encouraging. Probiotics in­creased poliovirus neutralizing an­tibody titers (NT) and affected the formation of poliovirus-specific IgA and IgG in serum. The maxi­mum increase after immunization was about 2, 2.2, or 4-fold higher, respectively, for NT, IgG or, IgA, in volunteers consuming probiotics instead of placebo. It was concluded that probi­otics induce an immunologic re­sponse that may provide enhanced systemic protection of cells from virus infections by increasing pro­duction of virus neutralizing anti­bodies. This study was conducted in Kiel , Germany in 2004.

A new clinical study published on line on September 7, 2011 in the acknowledged British Journal of Nutrition documents that Lactobacillus paracasei ssp . paracasei CRL431 or Bifidobacterium animalis ssp. lactis is an effective means to support the immune system. This study investigated the ability of these strains to modulate the immune syetem using a vaccination model in healthy subjects. A randomized, double-blind, placebo-controlled, parallel-group study was conducted in 211 subjects. Subjects consumed a minimum of 1 billion colony-forming units of either strain or matching placebo once daily for 6 weeks. After 2 weeks, influenza vaccination was given. Plasma and saliva samples were collected at baseline and after 6 weeks for the analysis of antibodies, cytokines and innate immune parameters. Changes from baseline in vaccine-specific plasma IgG, IgG1 and IgG3 were significantly greater in both groups v. the corresponding placebo group. The number of subjects obtaining a substantial increase in specific IgG was significantly greater in both groups v. placebo. Significantly greater mean fold increases for vaccine-specific secretory IgA in saliva were observed in both probiotic groups. Similar results were observed for total antibody concentrations. No differences were found for plasma cytokines or innate immune parameters. The key finding of the study indicate that daily consumption of at least one billion colony forming units of Lactobacillus paracasei ssp . paracasei CRL431 or Bifidobacterium animalis ssp. lactis may strengthen the immune system’s defense against common infections such as flu and colds. This study was conducted in Milano , Italy .

Each sachet of ResitonTM contains 1.0g (>3 billion CFU) of a standardized powder consisting of freeze-dried cultures of Lactobacillus paracasei subspecies paracasei .
– ResitonTM is recommended for the management, treatment and prevention of infections caused by viruses, bacteria or fungi of non-specific origin.
– ResitonTM can be used in conjunction with vaccines, including Polio vaccine to increase the production of virus neutralizing antibodies.
– ResitonTM is recommended for the prophylaxes of cold and flu symptoms.
– ResitonTM can be recommended in allergic conditions
– ResitonTM can be prescribed for atopic eczema
– ResitonTM can also be recommended in other secondary immunity deficiency symptoms

There is no specific contraindication for ResitonTM
Dosage and administration
The usual recommended dosage of ResitonTM for children and adults is 1-2 sachets a day. Consuming ResitonTM everyday for a long term helps maintain balanced intestinal flora and thus ensures good health. If required up to 8 sachets of ResitonTM can be recommended. If recommended with an anti-biotic, ResitonTM should be taken 2-3 hours before or after the anti-biotic administration. The contents of each sachet can be taken directly into the mouth or mixed with some normal water, beverage or semi liquid food.

Drug Interaction
There is no specific drug interaction associated with ResitonTM
Safety and Side Effects
ResitonTM is safe to use. It contains friendly bacteria that colonize in the intestinal tract and do not enter into the systemic circulation. In clinical studies no noticeable side effects have been noted which may be assumed as ResitonTM related.
Storage Condition
Store in a cool dry place. Protect from moisture, freezing, excessive heat and sunlight.
Each box contains 10 sachets.


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